The Grand Challenges in Global Health initiative is a partnership dedicated to supporting scientific and technical research to solve critical health problems in the developing world.  The initiative's partners are the Bill & Melinda Gates Foundation, the Canadian Institutes of Health Research, the Foundation for the National Institutes of Health, and the Wellcome Trust.

The Grand Challenges in Global Health initiative was established in 2002 as a way to galvanize and focus the scientific community to achieve scientific breakthroughs to fight diseases that kill millions of people each year in the world's poorest countries.

We were awarded a grant from the GCGH in 2005 to find ways to prevent or reduce the transmission of dengue virus using the developing tools of mosquito genetics.  While this work will not result in the release of modified mosquitoes into the environment, we are committed to understanding and addressing the ethical, social, and cultural issues that accompanies these efforts.  Research is now being carried out at institutions throughout the US and abroad.