The research program is investigating strategies for controlling the transmission of dengue viruses.  These strategies are predicated on the simple idea that if you can disrupt the ability of the mosquito to pass on the viruses, the transmission of the disease will be controlled.  The specific goal of this project is to test one or more control strategies in large cages in field conditions.  This project does NOT involve the release of any modified mosquitoes into the environment. 

The research program has three major Project Objectives.  Project Objectives include efforts to 1) introduce control DNA sequences and genes for mosquito population replacement and reduction; 2) develop safe and efficient systems for getting genes into mosquito populations in a reasonable time frame; and 3) develop a suitable containment cage to test alternate strategies and to generate feedback for modeling predictive outcomes at a location that fosters participation of dengue-endemic country partners.  A fourth Project Objective addresses Project Administration that provides overall management and organization.